Breast-cancer diagnosis with nipple fluid bFGF

被引：36

作者：

Liu, Y ^{[1
]}

Wang, JL ^{[1
]}

Chang, H ^{[1
]}

Barsky, SH ^{[1
]}

Nguyen, M ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Surg, Div Oncol, Los Angeles, CA 90095 USA

来源：

LANCET | 2000年 / 356卷 / 9229期

关键词：

D O I：

10.1016/S0140-6736(00)02587-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Early diagnosis of breast cancer is the key to extending survival of breast-cancer patients. We found that the concentrations of nipple fluid bFGF (basic fibroblast growth factor) was significantly increased in breast-cancer patients compared with concentrations in controls (1717 ng/L [SD 706] vs 19 ng/L [19]; Student's t test p=0.027). Measurement of bFGF in nipple fluid could be a useful diagnostic tool for breast cancer, and deserves further study.

引用

页码：567 / 567

页数：1

共 5 条

[1]

Foretova L, 1998, CANCER EPIDEM BIOMAR, V7, P195

[2]

Harris Jay, 1997, P1557

[3] Angiogenic factors as tumor markers [J].

Nguyen, M .

INVESTIGATIONAL NEW DRUGS, 1997, 15 (01) :29-37

[4] ELEVATED LEVELS OF AN ANGIOGENIC PEPTIDE, BASIC FIBROBLAST GROWTH-FACTOR, IN THE URINE OF PATIENTS WITH A WIDE SPECTRUM OF CANCERS [J].

NGUYEN, M ;

WATANABE, H ;

BUDSON, AE ;

RICHIE, JP ;

HAYES, DF ;

FOLKMAN, J .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1994, 86 (05) :356-361

[5]

Sauter ER, 1996, CANCER EPIDEM BIOMAR, V5, P967

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