Chronic Mycoplasma pneumoniae infection in a child after renal transplantation

被引：15

作者：

Schwerk, Nicolaus ^{[1
]}

Hartmann, Carolin ^{[1
]}

Baumann, Ulrich ^{[1
]}

Pape, Lars ^{[1
]}

Ehrich, Jochen H. H. ^{[1
]}

Hansen, Gesine ^{[1
]}

机构：

[1] Hannover Med Sch, Dept Pediat & Adolescent Med, D-30635 Hannover, Germany

来源：

PEDIATRIC TRANSPLANTATION | 2010年 / 14卷 / 03期

关键词：

Mycoplasma pneumoniae; renal transplantation; hypogammaglobulinemia; rituximab; fever; RESPIRATORY-TRACT INFECTIONS; POLYMERASE CHAIN-REACTION; PEDIATRIC-PATIENTS; RECIPIENTS; SIROLIMUS; DIAGNOSIS; KIDNEY;

D O I：

10.1111/j.1399-3046.2009.01130.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Mycoplasma pneumoniae has rarely been reported in renal transplant recipients. We present the case of a 10-yr-old boy with a six-month history of chronic cough, recurrent pyrexia, and weight loss three yr after RTx. The patient's post-transplant course was complicated by recurrence of NS that resolved with plasmapheresis and PTLD, which was successfully treated with an anti-CD20 monoclonal antibody. Chest X-ray showed a round mass-like lesion in the left upper lobe; MRT, PET, and bronchoscopy ruled out a PTLD. BAL fluid revealed M. pneumoniae-DNA. A three-wk course of macrolide therapy induced rapid recovery. We conclude that M. pneumoniae infection should be considered in immunosuppressed patients with long-lasting respiratory complaints and fever of unknown origin. Antibiotic treatment should be given for a minimum of three wk.

引用

页码：E26 / E29

页数：4

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