Palladium-catalysed cascade molecular queuing-cycloaddition, cyclocondensation and Diels-Alder reactions

被引：31

作者：

Grigg, R ^{[1
]}

Liu, A

Shaw, D

Suganthan, S

Washington, ML

Woodall, DE

Yoganathan, G

机构：

[1] Univ Leeds, Sch Chem, Mol Innovat Divers & Automated Synth, Leeds LS2 9JT, W Yorkshire, England

[2] Pharmacia & Upjohn Inc, Dept Chem, S-75182 Uppsala, Sweden

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 36期

基金：

英国工程与自然科学研究理事会;

关键词：

palladium catalysis; cascade reaction; cycloaddition; Diels-Alder reaction; azomethine ylides; nitrones; nitrile oxides; cyclocondensation;

D O I：

10.1016/S0040-4039(00)01177-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The locked s-cis enone system present in 3-methylenequinol-4-ones and chroman-4-ones offers substantial further synthetic opportunities as illustrated by the ability to function as a 2 pi-component in 1,3-dipolar cycloaddition reactions, or as a 2 pi- or 4 pi-component in Diels-Alder reactions. Cascade molecular queuing-cycloadditions/cyclocondensation are reported. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7129 / 7133

页数：5

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