Pd/Cu-catalyzed couplings of β-amino esters with aryl bromides.: Synthesis of chiral 1,2,3,4-tetrahydro-4-oxo-2-alkyl-1-quinolines

被引：17

作者：

Ma, DW ^{[1
]}

Jiang, JQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 07期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0957-4166(98)00078-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new protocol to prepare chiral 1,2,3,4-tetrahydro-4-oxo-2-alkyl-1-quinolines has been developed. The key steps are Pd/Cu-catalyzed couplings of chiral beta-amino esters and aryl bromides, and intramolecular acylation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1137 / 1142

页数：6

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