A microwave improvement in the synthesis of the quinazoline scaffold

被引：27

作者：

Chilin, Adriana ^{[1
]}

Marzaro, Giovanni ^{[1
]}

Zanatta, Samuele ^{[1
]}

Guiotto, Adriano ^{[1
]}

机构：

[1] Univ Padua, Dept Pharmaceut Sci, I-35131 Padua, Italy

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 18期

关键词：

quinazoline; microwave-assisted synthesis; irradiation cycles;

D O I：

10.1016/j.tetlet.2007.03.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rapid and efficient microwave-assisted protocol is described that greatly improves a recent synthetic method developed for quinazoline synthesis. The synthetic protocol is based on the use of cycles of microwave irradiation. The optimization process is reported and the experimental results are compared with those of the conventional synthetic route. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：3229 / 3231

页数：3

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