PINK1, a gene product of PARK6, accumulates in α-synucleinopathy brains

被引：24

作者：

Murakami, Tetsuro

Moriwaki, Yasuhiro

Kawarabayashi, Takeshi

Nagai, Makiko

Ohta, Yasuyuki

Deguchi, Kentaro

Kurata, Tomoko

Morimoto, Nobutoshi

Takehisa, Yasushi

Matsubara, Etsuro

Ikeda, Masaki

Harigaya, Yasuo

Shoji, Mikio

Takahashi, Ryosuke

Abe, Koji

机构：

[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Neurol, Okayama 7008558, Japan

[2] Kyoritsu Univ Pharm, Dept Clin Pharm, Div Pharmacol, Tokyo, Japan

[3] Natl Ctr Geriatr & Gerontol, Dept Alzheimers Dis Res, Natl Inst Longev Sci, Aichi, Japan

[4] Gunma Univ, Dept Neurol, Grad Sch Med, Gunma, Japan

[5] Maebashi Red Cross Hosp, Dept Neurol, Gunma, Japan

[6] Hirosaki Univ, Sch Med, Dept Neurol Sci, Inst Brain Sci, Hirosaki, Aomori 036, Japan

[7] Kyoto Univ, Dept Neurol, Grad Sch Med, Kyoto, Japan

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2007年 / 78卷 / 06期

关键词：

D O I：

10.1136/jnnp.2006.100123

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：653 / 655

页数：4

共 5 条

[1]

Baba M, 1998, AM J PATHOL, V152, P879

[2] PINK1 protein in normal human brain and Parkinson's disease [J].

Gandhi, S. ;

Muqit, M. M. K. ;

Stanyer, L. ;

Healy, D. G. ;

Abou-Sleiman, P. M. ;

Hargreaves, I. ;

Heales, S. ;

Ganguly, M. ;

Parsons, L. ;

Lees, A. J. ;

Latchman, D. S. ;

Holton, J. L. ;

Wood, N. W. ;

Revesz, T. .

BRAIN, 2006, 129 :1720-1731

[3] An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin [J].

Imai, Y ;

Soda, M ;

Inoue, H ;

Hattori, N ;

Mizuno, Y ;

Takahashi, R .

CELL, 2001, 105 (07) :891-902

[4] Pael-R is accumulated in Lewy bodies of Parkinson's disease [J].

Murakami, T ;

Shoji, M ;

Imai, Y ;

Inoue, H ;

Kawarabayashi, T ;

Matsubara, E ;

Harigaya, Y ;

Sasaki, A ;

Takahashi, R ;

Abe, K .

ANNALS OF NEUROLOGY, 2004, 55 (03) :439-442

[5] Hereditary early-onset Parkinson's disease caused by mutations in PINK1 [J].

Valente, EM ;

Abou-Sleiman, PM ;

Caputo, V ;

Muqit, MMK ;

Harvey, K ;

Gispert, S ;

Ali, Z ;

Del Turco, D ;

Bentivoglio, AR ;

Healy, DG ;

Albanese, A ;

Nussbaum, R ;

González-Maldonaldo, R ;

Deller, T ;

Salvi, S ;

Cortelli, P ;

Gilks, WP ;

Latchman, DS ;

Harvey, RJ ;

Dallapiccola, B ;

Auburger, G ;

Wood, NW .

SCIENCE, 2004, 304 (5674) :1158-1160

← 1 →