Light scattering study of rheumatoid arthritis

被引:24
作者
Beuthan, J
Netz, U
Minet, O
Klose, AD
Hielscher, AH
Scheel, A
Henniger, J
Müller, G
机构
[1] Free Univ Berlin, Inst Med Phys & Laser Med, D-14195 Berlin, Germany
[2] Columbia Univ, Dept Biomed Engn, New York, NY 10027 USA
[3] Univ Gottingen, Dept Med Nephrol & Rheumatol, D-37075 Gottingen, Germany
[4] Tech Univ Dresden, Dept Phys, D-01062 Dresden, Germany
关键词
biomedical functional imaging; near-infrared diaphanoscopy; optical diffusion tomography; rheumatic diseases; scattered light distribution;
D O I
10.1070/QE2002v032n11ABEH002326
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The distribution of light scattered by finger joints is studied in the near-IR region. It is shown that variations in the optical parameters of the tissue (scattering coefficient mus, absorption coefficient mua, and anisotropy factor g) depend on the presence of the rheumatoid arthritis (RA). At the first stage, the distribution of scattered light was measured in diaphanoscopic experiments. The convolution of a Gaussian error function with the scattering phase function proved to be a good approximation of the data obtained. Then, a new method was developed for the reconstruction of distribution of optical parameters in the finger cross section. Model tests of the quality of this reconstruction method show good results.
引用
收藏
页码:945 / 952
页数:8
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