Successful treatment of radiation nephropathy with angiotensin II blockade

被引：36

作者：

Cohen, EP

Hussain, S

Moulder, JE

机构：

[1] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Radiat Oncol, Milwaukee, WI 53226 USA

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2003年 / 55卷 / 01期

关键词：

radiation nephropathy; angiotensin; 2; hypertension; kidney transplant; glomerular filtration rate;

D O I：

10.1016/S0360-3016(02)03793-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: The aim of this report is to document the successful treatment of radiation nephropathy. Methods: Clinical case report with statistical analysis of evolution of kidney function. Results: A case of radiation nephropathy was found in a kidney transplant recipient whose kidney transplant had been irradiated with 750 cGy 23 years previously. Use of the angiotensin II blocker, losartan, was associated with significant stabilization of the kidney function. Conclusion: Radiation nephropathy can be successfully treated. Other normal-tissue radiation injuries may also be treatable. (C) 2003 Elsevier Science Inc.

引用

页码：190 / 193

页数：4

共 20 条

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