Liquid chromatography-tandem mass spectrometric analysis of surface and waste water with atmospheric pressure chemical ionisation - II. Applications

In Part I the design of the APCI interface and the scan modes of a triple quadrupole mass spectrometer have been described and general rules on how to use them have been discussed. Part II deals with the application of LC-APCI-MS/MS in the analysis of surface water and waste water. The goal is to analyse as many compounds as possible in one run. First, attention is paid to the LC part of the system to provide a good fit with the APCI interface, and the application and settings of the scan modes available. Next, results from the methods developed are shown, and matters such as their sensitivity and applicability are discussed. Finally, a CI-CID spectrum library concept is presented and discussed, which aims to solve the problem of the identification of unknown compounds. (C) 2000 Elsevier Science B.V. All rights reserved.