Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastases

被引：5

作者：

Chang, Yueh-Shih ^{[1
]}

Huang, Jen-Seng ^{[1
]}

Yen, Cho-Li ^{[2
]}

Chien, Rong-Nan ^{[2
]}

Wang, Cheng-Hsu ^{[1
]}

Lai, Chien-Hong ^{[1
]}

Wu, Tsung-Han ^{[1
]}

Lan, Yii-Jeng ^{[1
]}

Yeh, Kun-Yun ^{[1
]}

机构：

[1] Keelung & Chang Gung Univ, Chang Gung Mem Hosp, Dept Internal Med, Div Hematooncol, Keelung, Taiwan

[2] Keelung Chang Gung Mem Hosp, Dept Internal Med, Div Hepatogastroenterol, Liver Res Unit, Keelung, Taiwan

来源：

ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION | 2017年 / 26卷 / 04期

关键词：

hepatocellular carcinoma; body mass index; 6-month survival; metastasis; extrahepatic; NONALCOHOLIC FATTY LIVER; CLINICAL-FEATURES; OBESITY; DISEASE; IMPACT; RISK;

D O I：

10.6133/apjcn.062016.03

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Background and Objectives: To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC). Methods and Study Design: We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] >24 kg/m(2)), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis. Results: BMI>24 kg/m(2) was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration >3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI >24 kg/m(2) was an independent prognostic factor for the 6-month survival rate (p=0.03). Conclusions: BMI >24 kg/m(2) was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.

引用

页码：637 / 641

页数：5

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