Neuroimaging predictors of onset and course of depression in childhood and adolescence: A systematic review of longitudinal studies

被引:58
作者
Toenders, Yara J. [1 ,2 ]
van Velzen, Laura S. [1 ,2 ]
Heideman, Ivonne Z. [1 ]
Harrison, Ben J. [3 ,4 ]
Davey, Christopher G. [1 ,2 ]
Schmaal, Lianne [1 ,2 ]
机构
[1] Orygen, 35 Poplar Rd, Parkville, Vic 3052, Australia
[2] Univ Melbourne, Ctr Youth Mental Hlth, 35 Poplar Rd, Parkville, Vic 3052, Australia
[3] Univ Melbourne, Dept Psychiat, Melbourne Neuropsychiat Ctr, Level 3,Alan Gilbert Bldg,161 Barry St, Carlton, Vic 3053, Australia
[4] Melbourne Hlth, Level 3,Alan Gilbert Bldg,161 Barry St, Carlton, Vic 3053, Australia
基金
澳大利亚国家健康与医学研究理事会; 美国国家卫生研究院;
关键词
Depression; Adolescence; Childhood; Neuroimaging; Prediction; HIGH-FAMILIAL RISK; CORTICAL THICKNESS MATURATION; ANTERIOR CINGULATE CORTEX; BLUNTED NEURAL RESPONSE; NEGATIVE LIFE EVENTS; AGE-OF-ONSET; FUNCTIONAL CONNECTIVITY; MAJOR DEPRESSION; ORBITOFRONTAL CORTEX; BRAIN-DEVELOPMENT;
D O I
10.1016/j.dcn.2019.100700
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Major depressive disorder (MDD) often emerges during adolescence with detrimental effects on development as well as lifetime consequences. Identifying neurobiological markers that are associated with the onset or course of this disorder in childhood and adolescence is important for early recognition and intervention and, potentially, for the prevention of illness onset. In this systematic review, 68 longitudinal neuroimaging studies, from 34 unique samples, that examined the association of neuroimaging markers with onset or changes in paediatric depression published up to 1 February 2019 were examined. These studies employed different imaging modalities at baseline; structural magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), functional MRI (fMRI) or electroencephalography (EEG). Most consistent evidence across studies was found for blunted reward-related (striatal) activity (fMRI and EEG) as a potential biological marker for both MDD onset and course. With regard to structural brain measures, the results were highly inconsistent, likely caused by insufficient power to detect complex mediating effects of genetic and environmental factors in small sample sizes. Overall, there were a limited number of samples, and confounding factors such as sex and pubertal development were often not considered, whereas these factors are likely to be relevant especially in this age range.
引用
收藏
页数:17
相关论文
共 142 条
[1]   Age-related volumetric change of limbic structures and subclinical anxious/depressed symptomatology in typically developing children and adolescents [J].
Albaugh, Matthew D. ;
Tuong-Vi Nguyen ;
Ducharme, Simon ;
Collins, D. Louis ;
Botteron, Kelly N. ;
D'Alberto, Nicholas ;
Evans, Alan C. ;
Karama, Sherif ;
Hudziaka, James J. .
BIOLOGICAL PSYCHOLOGY, 2017, 124 :133-140
[2]   An open resource for transdiagnostic research in pediatric mental health and learning disorders [J].
Alexander, Lindsay M. ;
Escalera, Jasmine ;
Ai, Lei ;
Andreotti, Charissa ;
Febre, Karina ;
Mangone, Alexander ;
Vega-Potler, Natan ;
Langer, Nicolas ;
Alexander, Alexis ;
Kovacs, Meagan ;
Litke, Shannon ;
O'Hagan, Bridget ;
Andersen, Jennifer ;
Bronstein, Batya ;
Bui, Anastasia ;
Bushey, Marijayne ;
Butler, Henry ;
Castagna, Victoria ;
Camacho, Nicolas ;
Chan, Elisha ;
Citera, Danielle ;
Clucas, Jon ;
Cohen, Samantha ;
Dufek, Sarah ;
Eaves, Megan ;
Fradera, Brian ;
Gardner, Judith ;
Grant-Villegas, Natalie ;
Green, Gabriella ;
Gregory, Camille ;
Hart, Emily ;
Harris, Shana ;
Horton, Megan ;
Kahn, Danielle ;
Kabotyanski, Katherine ;
Karmel, Bernard ;
Kelly, Simon P. ;
Kleinman, Kayla ;
Koo, Bonhwang ;
Kramer, Eliza ;
Lennon, Elizabeth ;
Lord, Catherine ;
Mantello, Ginny ;
Margolis, Amy ;
Merikangas, Kathleen R. ;
Milham, Judith ;
Minniti, Giuseppe ;
Neuhaus, Rebecca ;
Levine, Alexandra ;
Osman, Yael .
SCIENTIFIC DATA, 2017, 4
[3]   Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort [J].
Allan, Charlotte L. ;
Sexton, Claire E. ;
Filippini, Nicola ;
Topiwala, Anya ;
Mahmood, Abda ;
Zsoldos, Eniko ;
Singh-Manoux, Archana ;
Shipley, Martin J. ;
Kivimaki, Mika ;
Mackay, Clare E. ;
Ebmeier, Klaus P. .
JOURNAL OF AFFECTIVE DISORDERS, 2016, 204 :219-225
[4]   The anterior cingulate cortex - The evolution of an interface between emotion and cognition [J].
Allman, JM ;
Hakeem, A ;
Erwin, JM ;
Nimchinsky, E ;
Hof, P .
UNITY OF KNOWLEDGE: THE CONVERGENCE OF NATURAL AND HUMAN SCIENCE, 2001, 935 :107-117
[5]   Organizing Principles of Human Cortical Development-Thickness and Area from 4 to 30 Years: Insights from Comparative Primate Neuroanatomy [J].
Amlien, Inge K. ;
Fjell, Anders M. ;
Tamnes, Christian K. ;
Grydeland, Hakon ;
Krogsrud, Stine K. ;
Chaplin, Tristan A. ;
Rosa, Marcello G. P. ;
Walhovd, Kristine B. .
CEREBRAL CORTEX, 2016, 26 (01) :257-267
[6]   Pubertal changes in hormone levels and depression in girls [J].
Angold, A ;
Costello, EJ ;
Erkanli, A ;
Worthman, CM .
PSYCHOLOGICAL MEDICINE, 1999, 29 (05) :1043-1053
[7]  
[Anonymous], 2017, Data requirements and methods to support the evaluation of new vector control products
[8]   Neuroanatomical Prediction of Anhedonia in Adolescents [J].
Auerbach, Randy P. ;
Pisoni, Angela ;
Bondy, Erin ;
Kumar, Poornima ;
Stewart, Jeremy G. ;
Yendiki, Anastasia ;
Pizzagalli, Diego A. .
NEUROPSYCHOPHARMACOLOGY, 2017, 42 (10) :2087-2095
[9]   Circuitry and functional aspects of the insular lobe in primates including humans [J].
Augustine, JR .
BRAIN RESEARCH REVIEWS, 1996, 22 (03) :229-244
[10]   Cognitive deficits in depression - Possible implications for functional neuropathology [J].
Austin, MP ;
Mitchell, P ;
Goodwin, GM .
BRITISH JOURNAL OF PSYCHIATRY, 2001, 178 :200-206