Effects of housing conditions and 5-HT2A activation on male rat sexual behavior

被引:26
作者
Brotto, LA [1 ]
Gorzalka, BB [1 ]
Hanson, LA [1 ]
机构
[1] Univ British Columbia, Dept Psychol, Vancouver, BC V6T 1Z4, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
5-HT2A receptors; isolation; serotonin; sexual activity; stress;
D O I
10.1016/S0031-9384(97)00482-4
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Adult male rats were housed individually or in groups for a period of 39 days. In Experiment 1, the effects of housing conditions on sexual behavior and concurrent spontaneous "wet dog shaking" (WDS) were investigated. Individual housing significantly impaired male sexual behavior and resulted in a trend toward increased WDS. In Experiment 2, the effects of housing conditions were examined following administration of the serotonergic type 2A (5-HT2A) agonist DOI. Individual housing significantly increased DOI-induced WDS. The implications of these findings are discussed in the context of stress-induced corticosterone secretion and the possible regulatory effect on 5-HT2A receptors. (C) 1998 Elsevier Science Inc.
引用
收藏
页码:475 / 479
页数:5
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