Working memory in medicated patients with Parkinson's disease: The central executive seems to work

被引:33
作者
Fournet, N
Moreaud, O
Roulin, JL
Naegele, B
Pellat, J
机构
[1] CHU GRENOBLE,SERV NEUROL & NEUROCHIRURG,F-38043 GRENOBLE,FRANCE
[2] UNIV SAVOIE,CHAMBERY,FRANCE
关键词
Parkinson's disease; working memory; attention; frontal lobe;
D O I
10.1136/jnnp.60.3.313
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective-To determine whether a deficit of the central executive can explain the attentional deficits of patients with Parkinson's disease. Methods-Fifteen patients with idiopathic Parkinson's disease and 15 controls were given a dual task paradigm minimising motor demands and combining verbal, visual, or spatial span with two conditions of articulatory suppression. Results-Although the spans were systematically lower in medicated parkinsonian patients than in controls, suggesting a decrease of central processing resources, there was no direct evidence for a deficit of the central executive. Conclusions-A deficit of the central executive either is not an inevitable feature of the disease, or is dependent on the nature of task (visuomotor v cognitive), or is corrected by dopaminergic medication.
引用
收藏
页码:313 / 317
页数:5
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