The paradoxical relationship between NHEJ and telomeric fusion

被引:13
作者
Williams, B [1 ]
Lustig, AJ [1 ]
机构
[1] Tulane Univ, Dept Biochem, Hlth Sci Ctr, New Orleans, LA 70112 USA
关键词
D O I
10.1016/S1097-2765(03)00200-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent results shed new light on the origin of fusion products observed in the destabilized chromosomes of cancer and related diseases. These findings define an unusual relationship between nonhomologous end joining (NHEJ) and telomere "capping," with identical proteins playing opposing roles.
引用
收藏
页码:1125 / 1126
页数:2
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