Endometriosis in monozygotic twins

被引:131
作者
Hadfield, RM [1 ]
Mardon, HJ [1 ]
Barlow, DH [1 ]
Kennedy, SH [1 ]
机构
[1] UNIV OXFORD,JOHN RADCLIFFE HOSP,NUFFIELD DEPT OBSTET & GYNAECOL,OXFORD OX3 9DU,ENGLAND
关键词
endometriosis; genetics; twins;
D O I
10.1016/S0015-0282(97)00359-2
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To describe the occurrence of endometriosis in monozygotic twins. Design: Postal questionnaire plus confirmation of disease status. Setting: Twins were recruited via the American Endometriosis Association and the National Endometriosis Society of Great Britain and via British gynecologists. Result(s): Fourteen twin pairs were concordant for endometriosis, and two were discordant. Nine pairs of twins had moderate-severe endometriosis. Conclusion(s): These findings contribute to the growing body of literature that suggests endometriosis has a genetic basis. (C) 1997 by American Society for Reproductive Medicine.
引用
收藏
页码:941 / 942
页数:2
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