Opioid tolerance and hyperalgesia

被引：137

作者：

Chang, Grace ^{[1
]}

Chen, Lucy ^{[1
]}

Mao, Jianren ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Pain Ctr,Div Pain Med,Dept Anesthesia & Crit Care, Boston, MA 02114 USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2007年 / 91卷 / 02期

关键词：

D O I：

10.1016/j.mcna.2006.10.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Opioids have been successfully used for the management of acute and cancer-related pain. Concerns regarding side effects, tolerance, dependence, addiction, and hyperalgesia have limited the use of opioids for the management of chronic nonmalignant pain. This article will review updated information from both clinical and preclinical studies regarding opioid-induced hyperalgesia, tolerance, and dependence. The implications of these issues in clinical opioid therapy also will be discussed.

引用

收藏

页码：199 / +

页数：14

相关论文

共 47 条

[1] CLINICAL-EXPERIENCE OF LONG-TERM TREATMENT WITH EPIDURAL AND INTRATHECAL OPIOIDS - A NATIONWIDE SURVEY [J].

ARNER, S ;

RAWAL, N ;

GUSTAFSSON, LL .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1988, 32 (03) :253-259

[2] THE COGNITIVE EFFECTS OF THE ADMINISTRATION OF NARCOTIC ANALGESICS IN PATIENTS WITH CANCER PAIN [J].

BRUERA, E ;

MACMILLAN, K ;

HANSON, J ;

MACDONALD, RN .

PAIN, 1989, 39 (01) :13-16

[3] Long-lasting hyperalgesia induced by fentanyl in rats -: Preventive effect of ketamine [J].

Célèrier, E ;

Rivat, C ;

Jun, Y ;

Laulin, JP ;

Larcher, A ;

Reynier, P ;

Simonnet, G .

ANESTHESIOLOGY, 2000, 92 (02) :465-472

[4] Progressive enhancement of delayed hyperalgesia induced by repeated heroin administration:: A sensitization process [J].

Célèrier, E ;

Laulin, JP ;

Corcuff, JB ;

Le Moal, M ;

Simonnet, G .

JOURNAL OF NEUROSCIENCE, 2001, 21 (11) :4074-4080

[5] Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: A preliminary prospective study [J].

Chu, LF ;

Clark, DJ ;

Angst, MS .

JOURNAL OF PAIN, 2006, 7 (01) :43-48

[6]

COCHIN J, 1964, J PHARMACOL EXP THER, V145, P1

[7] Opioid tolerance: the clinical perspective [J].

Collett, BJ .

BRITISH JOURNAL OF ANAESTHESIA, 1998, 81 (01) :58-68

[8] Pain intolerance in opioid-maintained former opiate addicts: effect of long-acting maintenance agent [J].

Compton, P ;

Charuvastra, VC ;

Ling, W .

DRUG AND ALCOHOL DEPENDENCE, 2001, 63 (02) :139-146

[9] Pain responses in methadone-maintained opioid abusers [J].

Compton, P ;

Charuvastra, VC ;

Kintaudi, K ;

Ling, W .

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2000, 20 (04) :237-245

[10] Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgery [J].

Crawford, MW ;

Hickey, C ;

Zaarour, C ;

Howard, A ;

Naser, B .

ANESTHESIA AND ANALGESIA, 2006, 102 (06) :1662-1667

← 1 2 3 4 5 →