Acute neurologic decompensation in an infant with cobalamin deficiency exposed to nitrous oxide

被引：33

作者：

Felmet, K

Robins, B

Tilford, D

Hayflick, SJ

机构：

[1] Oregon Hlth Sci Univ, Dept Pediat, Portland, OR 97201 USA

[2] Oregon Hlth Sci Univ, Dept Anesthesiol, Portland, OR 97201 USA

[3] Oregon Hlth Sci Univ, Dept Mol & Med Genet, Portland, OR 97201 USA

来源：

JOURNAL OF PEDIATRICS | 2000年 / 137卷 / 03期

关键词：

D O I：

10.1067/mpd.2000.107387

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

After exposure to nitrous oxide, an infant with unrecognized cobalamin deficiency developed neurologic deterioration and pancytopenia. Hematologic recovery and partial resolution of his neurologic changes followed repletion of the vitamin. Nitrous oxide depletes bioavailable cobalamin and may be a dangerous anesthetic in patients with cobalamin deficiency.

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页码：427 / 428

页数：2

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