Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus

被引：36

作者：

Inghilleri, M

Mattia, D

Berardelli, A

Manfredi, M

机构：

[1] Univ Rome La Sapienza, Dept Neurol Sci, I-00185 Rome, Italy

[2] Inst Neurol Mediterraneo Neuromed, Pozzilli, Italy

来源：

ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1998年 / 109卷 / 01期

关键词：

cortical excitability; transcranial stimulation; focal motor epilepsy; cortical myoclonus;

D O I：

10.1016/S0924-980X(97)00062-3

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Motor cortex excitability was analyzed with transcranial stimulation in a patient with motor focal epilepsy and cortical myoclonus originating from the right motor cortex. The motor threshold to single transcranial magnetic shocks, but not to electric stimuli, was higher in the epileptic motor cortex than the normal left motor cortex. Single magnetic shocks elicited a short cortical silent period (50 ms) in the epileptic motor cortex. Paired magnetic stimuli also showed reduced cortico-cortical inhibition. These findings reveal an asymmetry in cortical excitability presumably due to impaired inhibition in the epileptic motor cortex. (C) 1998 Elsevier Science Ireland Ltd.

引用

页码：70 / 72

页数：3

共 8 条

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BERARDELLI A, 1991, CURR OPIN NEUROL NEU, V4, P770

[2] Abnormalities of the balance between inhibition and excitation in the, motor cortex of patients with cortical myoclonus [J].