Development of a catalytic cycle for the generation of C1-glycosyl carbanions with Cp2TiCl2:: application to glycal synthesis

被引：31

作者：

Hansen, T ^{[1
]}

Daasbjerg, K ^{[1
]}

Skrydstrup, T ^{[1
]}

机构：

[1] Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 44期

关键词：

electron transfer; glycosyl halides; anomeric radicals; anions; titanium;

D O I：

10.1016/S0040-4039(00)01514-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic cycle has been developed for the conversion of glycosyl halides to their corresponding glycals using Cp2TiCl2. This process can be effectively used with only 30% of the in situ generated single electron reducing agent in contrast to the 2 equivalents normally employed. (C) 2000 Published by Elsevier Science Ltd.

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收藏

页码：8645 / 8649

页数：5

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