Epithelial NF-κB maintains host gut microflora homeostasis

被引：32

作者：

Ben-Neriah, Yinon ^{[1
]}

Schmidt-Supprian, Marc

机构：

[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Lautenberg Ctr Immunol, IL-91220 Jerusalem, Israel

[2] CBR Inst Biomed Res, Boston, MA 02115 USA

来源：

NATURE IMMUNOLOGY | 2007年 / 8卷 / 05期

关键词：

D O I：

10.1038/ni0507-479

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Epithelial NF-kappa B preserves the integrity of the gut epithelial barrier and coordinates the antimicrobial actions of the innate and adaptive immune systems. Deficiency in or hyperactivation of this transcription factor results in chronic inflammatory bowel disease.

引用

页码：479 / 481

页数：3

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