Epidemiology of benign paroxysmal positional vertigo: a population based study

被引:820
作者
von Brevern, M.
Radtke, A.
Lezius, F.
Feldmann, M.
Ziese, T.
Lempert, T.
Neuhauser, H.
机构
[1] Charite, Neurol Klin, D-13353 Berlin, Germany
[2] Robert Koch Inst, D-1000 Berlin, Germany
[3] Schlosspk Klin, Dept Neurol, Berlin, Germany
关键词
D O I
10.1136/jnnp.2006.100420
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: To examine the prevalence and incidence, clinical presentation, societal impact and comorbid conditions of benign paroxysmal positional vertigo (BPPV) in the general population. Methods: Cross-sectional, nationally representative neurotological survey of the general adult population in Germany with a two stage sampling design: screening of 4869 participants from the German National Telephone Health Interview Survey 2003 (response rate 52%) for moderate or severe dizziness or vertigo, followed by validated neurotological interviews (n = 1003; response rate 87%). Diagnostic criteria for BPPV were at least five attacks of vestibular vertigo lasting,1 min without concomitant neurological symptoms and invariably provoked by typical changes in head position. In a concurrent validation study (n = 61) conducted in two specialised dizziness clinics, BPPV was detected by our telephone interview with a specificity of 92% and a sensitivity of 88% (positive predictive value 88%, negative predictive value 92%). Results: BPPV accounted for 8% of individuals with moderate or severe dizziness/vertigo. The lifetime prevalence of BPPV was 2.4%, the 1 year prevalence was 1.6% and the 1 year incidence was 0.6%. The median duration of an episode was 2 weeks. In 86% of affected individuals, BPPV led to medical consultation, interruption of daily activities or sick leave. In total, only 8% of affected participants received effective treatment. On multivariate analysis, age, migraine, hypertension, hyperlipidaemia and stroke were independently associated with BPPV. Conclusion: BPPV is a common vestibular disorder leading to significant morbidity, psychosocial impact and medical costs.
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页码:710 / 715
页数:6
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