Frequency of fruit and vegetable consumption and coronary heart disease in France and Northern Ireland:: the PRIME study

被引:82
作者
Dauchet, L
Ferrières, J
Arveiler, D
Yarnell, JW
Gey, F
Ducimetière, P
Ruidavets, JB
Haas, B
Evans, A
Bingham, A
Amouyel, P
Dallongeville, J
机构
[1] Inst Pasteur, INSERM, U508, MONICA Lille, F-59019 Lille, France
[2] Fac Med Purpan, INSERM, U558, MONICA Toulouse, Toulouse, France
[3] Lab Epidemiol & Sante Publ, MONICA Strasbourg, Strasbourg, France
[4] Queens Univ Belfast, Dept Epidemiol & Publ Hlth, Belfast MONICA, Belfast, Antrim, North Ireland
[5] Univ Bern, Vitamin Res Unit, CH-3012 Bern, Switzerland
[6] Hop Paul Brousse, INSERM, U258, Villejuif, France
关键词
fruit; vegetable; coronary heart disease; epidemiological cohort study;
D O I
10.1079/BJN20041286
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Fruit and vegetable consumption is associated with low CHD risk in the USA and Northern Europe. There is, in contrast, little information about these associations in other regions of Europe. The goal of the present study was to assess the relationship between frequency of fruit and vegetable intake and CHD risk in two European populations with contrasting cardiovascular incidence rates; France and Northern Ireland. The present prospective study was in men aged 50-59 years, free of CHD, who were recruited in France (n 5982) and Northern Ireland (n 2105). Fruit and vegetable intake was assessed by a food-frequency questionnaire. Incident cases of acute coronary events and angina were recorded over a 5-year follow-up. During follow-up there was a total of 249 ischaemic events. After adjustment on education level, smoking, physical activity, alcohol consumption, employment status, BMI, blood pressure, serum total and HDL-cholesterol, the relative risks (RR) of acute coronary events were 0.67 (95 % CI 0.44, 1.03) and 0.64 (95 % CI 0.41, 0.99) in the 2nd and 3rd tertiles of citrus fruit consumption, respectively (P for trend <0.03). Similar results were observed in France and Northern Ireland. In contrast, the RR of acute coronary events for 'other fruit' consumption were 0.70 (95 % CI 0.31, 1.56) and 0.52 (95 % CI 0.24, 1.14) respectively in Northern Ireland (trend P<0.05) and 1.29 (95 % CI 0.69, 2.4) and 1.15 (95 % CI 0.68, 1.94) in France (trend P=0.5; interaction P<0.04). There was no evidence for any association between vegetable intake and total CHD events. In conclusion, frequency of citrus fruit, but not other fruits, intake is associated with lower rates of acute coronary events in both France and Northern Ireland, suggesting that geographical or related factors might affect the relationship between fruit consumption and CHD risk.
引用
收藏
页码:963 / 972
页数:10
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