High prevalence of GB virus C/hepatitis G virus RNA and antibodies in patients infected with human immunodeficiency virus type 1

被引：36

作者：

Rey, D

Vidinic-Moularde, J

Meyer, P

Schmitt, C

Fritsch, S

Lang, JM

Stoll-Keller, F

机构：

[1] Hop Univ, CISIH, Clin Med A, F-67091 Strasbourg, France

[2] Fac Med Strasbourg, Inst Virol, F-67000 Strasbourg, France

[3] Hop Univ, Dept Med Informat, F-67091 Strasbourg, France

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2000年 / 19卷 / 09期

关键词：

D O I：

10.1007/s100960000352

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) RNA and antibodies to the structural E2 protein was investigated in a cohort of HIV-1 infected patients. Of 346 individuals, RNA was detected in 143 and E2 antibodies were detected in 73, for an overall prevalence of 62,4%. Intravenous drug use and homosexuality were identified as major transmission risk factors. GBV-C/HGV RNA prevalence was associated with hepatitis B coinfection, whereas antibodies to E2 were associated with older age and lower CD4+ cell counts. GBV-C/HGV infection was frequent in this group of HIV-infected patients and was associated with older age, lower CD4+ cell counts, and the presence of hepatitis B surface antigen.

引用

页码：721 / 724

页数：4