Cell polarity: Par6, aPKC and cytoskeletal crosstalk

被引：246

作者：

Etienne-Manneville, S ^{[1
]}

Hall, A ^{[1
]}

机构：

[1] UCL, MRC, Mol Cell Biol Lab, London WC1E 6BT, England

来源：

CURRENT OPINION IN CELL BIOLOGY | 2003年 / 15卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0955-0674(02)00005-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Par6 and atypical protein kinase C are key players in the establishment of cell polarity. First discovered in Caenorhabditis elegans, the function of this protein complex in all multicellular organisms. Recent work is beginning to throw light on how it converts information generated by extracellular cues into intracellular asymmetry.

引用

页码：67 / 72

页数：6

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