Implication of the prohead RNA in phage φ29 DNA packaging

被引：14

作者：

Bourassa, N

Major, F

机构：

[1] Univ Montreal, Dept Informat & Rech Operat, Montreal, PQ H3C 3J7, Canada

[2] Univ Montreal, Dept Biochim, Montreal, PQ H3C 3J7, Canada

来源：

BIOCHIMIE | 2002年 / 84卷 / 09期

基金：

加拿大健康研究院;

关键词：

bacteriophage phi 29; prohead; RNA; connector; multimer; computer modeling; MC-Sym;

D O I：

10.1016/S0300-9084(02)01444-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA is an important component of many biological processes, including DNA encapsidation of bacteriophage phi29 of Bacillus subtilis. Interestingly, the prohead RNA is involved, in this encapsidation, and was found in monomer, dimer, pentamer and hexamer conformations. This article presents and debates current knowledge about the prohead RNA structures, mechanisms, and roles in DNA encapsidation. A new dimer structure is presented, and its specific role in DNA encapsidation is discussed. (C) 2002 Societe francaise de biochimie et biologie moleculaire/Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：945 / 951

页数：7

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