Sulfonylamidation of alkylbenzenes at benzylic position with p-toluenesulfonamide and 1,3-diiodo-5,5-dimethylhydantoin

被引：15

作者：

Baba, Haruka ^{[1
]}

Togo, Hideo ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Sci, Inage Ku, Chiba 2638522, Japan

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 15期

关键词：

1,3-Diiodo-5,5-dimethylhydantoin; Alkylbenzene; p-Toluenesulfonamide; alpha-(p-Toluenesulfonylamido)alkylbenzene; Sulfonamidyl radical; HYPERVALENT IODINE REAGENTS; ANOMERIC ALKOXY RADICALS; FRAGMENTATION-INTRAMOLECULAR FUNCTIONALIZATION; BETA-FRAGMENTATION; OXIDATIVE CONVERSION; ORGANIC-SYNTHESIS; CYCLOPEROXYIODINATION REACTION; IODOSOBENZENE DIACETATE; HETEROCYCLIC-COMPOUNDS; ORGANOIODINE REAGENTS;

D O I：

10.1016/j.tetlet.2010.02.060

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

Treatment of alkylbenzenes with p-toluenesulfonamide and 1,3-diiodo-5,5-dimethylhydantoin (DIH) in a small amount of carbon tetrachloride at 60 degrees C gave the corresponding alpha-p-toluenesulfonylamido)alkylbenzenes in good to moderate yields. The present reaction is a simple method for the alpha-sulfonylamidation of the benzylic position in alkylbenzenes. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：2063 / 2066

页数：4

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