easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses

被引：159

作者：

Lindner, TH ^{[1
]}

Hoffmann, K

机构：

[1] Univ Wurzburg, Med Univ Clin, Dept Med, Div Nephrol, Wurzburg, Germany

[2] Univ Wurzburg, Med Univ Clin, Dept Clin Biochem & Pathobiochem, Wurzburg, Germany

[3] Humboldt Univ, Charite, Inst Med Genet, D-13353 Berlin, Germany

来源：

BIOINFORMATICS | 2005年 / 21卷 / 03期

关键词：

D O I：

10.1093/bioinformatics/bti009

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We have generated the program easyLINKAGE that combines automated setup and performance of linkage analyses and simulation under an easy to handle graphical user interface for Microsoft Windows 2000/XP and standard UNIX systems. The program package supports two-point linkage analyses (FastLink v4.1 and SPLink v1.09), multi-point linkage analyses [GENEHUNTER v2.1, GENEHUNTER-PLUS with the emendation by Kong and Cox v1.2 (allele sharing modelling)] and the simulation package SLINK v2.65, and provides genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters.

引用

页码：405 / 407

页数：3

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