The genus Scutellaria an ethnopharmacological and phytochemical review

被引：355

作者：

Shang, Xiaofei ^{[1
,2
]}

He, Xirui ^{[1
,3
]}

He, Xiaoying ^{[1
]}

Li, Maoxing ^{[1
]}

Zhang, Ruxue ^{[1
]}

Fan, Pengcheng ^{[1
]}

Zhang, Quanlong ^{[1
]}

Jia, Zhengping ^{[1
]}

机构：

[1] Lanzhou Gen Hosp PLA, Dept Pharm, Lanzhou 730050, Peoples R China

[2] Lanzhou Univ, Dept Life Sci, Lanzhou 730000, Peoples R China

[3] Lanzhou Univ, Dept Pharm, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2010年 / 128卷 / 02期

关键词：

Scutellaria; Ethnopharmacology; Phytochemistry; Flavonoids; Antitumor; Hepatoprotective; NEPALESE CRUDE DRUGS; NEOCLERODANE-TYPE DITERPENOIDS; INDUCED CYCLOOXYGENASE-2 EXPRESSION; HUMAN CANCER-CELLS; FLAVONOID CONSTITUENTS; BAICALENSIS GEORGI; ANTIMICROBIAL ACTIVITY; MEDICINAL HERBS; PLANT FLAVONE; IN-VIVO;

D O I：

10.1016/j.jep.2010.01.006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Scutellaria (HUANG QIN) (Lamiaceae), which includes about 350 species commonly known as skullcaps. is widespread in Europe, the United States and East Asia Some species are taken to clear away the heat-evil and expel superficial evils in traditional Chinese medicine (TCM) The present paper reviews the ethnopharmacology, the biological activities and the correlated chemical compounds of Scutelloria species More than 295 compounds have been isolated, among them flavonoids and diterpenes. Studies show that Scutellaria and its active principles possess wide pharmacological actions, such as antitumor, anti-angiogenesis, hepatoprotective. antioxidant, anticonvulsant, antibacterial and antiviral activities Currently, effective monomeric compounds or active parts have been screened for pharmacological activity from Scutellaria in vivo and in vitro Increasing data supports application and exploitation for new drug development (C) 2010 Elsevier Ireland Ltd All rights reserved

引用

页码：279 / 313

页数：35

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