Redoxing calcium from the ER

被引：11

作者：

Roderick, HL ^{[1
]}

Bootman, MD ^{[1
]}

机构：

[1] Babraham Inst, Mol Signalling Lab, Cambridge CB2 4AT, England

来源：

CELL | 2005年 / 120卷 / 01期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/j.cell.2004.12.034

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inositol 1,4,5-trisphosphate (InsP(3))-induced calcium release from the endoplasmic reticulum (ER) intracellular calcium store regulates cellular functions from the beginning of life at fertilization until death. In this issue of Cell, Mikoshiba and colleagues describe a novel mode of regulation of the InsP(3) receptor (InsP(3)R) governed by ER luminal redox status, calcium, and pH (Higo et al., 2005).

引用

页码：4 / 5

页数：2

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