Novel synthesis of benzo[a]quinolizines (pyrido[2,1-a]isoquinolines) by [3+3]-cyclocondensation of 1-alkyl-3,4-dihydroisoquinolines with β-ketoesters

被引：1

作者：

Gulyakevich, OV ^{[1
]}

Kurman, PV ^{[1
]}

Mikhal'chuk, AL ^{[1
]}

机构：

[1] Natl Acad Sci, Inst Bioorgan Chem, Minsk, BELARUS

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2002年 / 38卷 / 06期

关键词：

synthesis; 1-alkyl-3,4-dihydroisoquinoline, acetoacetic and 2-benzylacetoacetic esters; benzo[a]quinolizine (pyrido[2,1-a]isoquinoline);

D O I：

10.1023/A:1022607325613

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Benzo[a]quinolizines (pyrido[2,1-a]isoquinolines) were synthesized via heterocyclization of 1-alkyldihydroisoquinoline Schiff bases with beta-ketoesters.

引用

页码：598 / 601

页数：4

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