Vitamin E and C in preeclampsia

被引：67

作者：

Kharb, S ^{[1
]}

机构：

[1] Pt BD Sharma PGIMS, Dept Biochem, Rohtak, Haryana, India

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2000年 / 93卷 / 01期

关键词：

vitamin C; vitamin E; antioxidants; free radicals; preeclampsia;

D O I：

10.1016/S0301-2115(00)00243-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Vascular endothelial damage has been implicated in the pathophysiology of preeclampsia. Lipid peroxidation may be involved in the process and essential nutrients that can scavenge free radicals, such as vitamin E and C, operate in concert. Antioxidant vitamins E and C were estimated in 30 preeclamptic and 30 normotensive pregnant women. Significantly lowered levels of vitamins E and C were observed in preeclamptic women as compared to controls (P<0.001 and P<0.05 respectively). In patients with preeclampsia antioxidant nutrients may be utilized to a greater extent to counteract free radical-mediated cell disturbances, resulting in a reduction in serum antioxidant levels. (C) 2000 Elsevier Science ireland Ltd. All rights reserved.

引用

页码：37 / 39

页数：3

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