A license to remember

被引:9
作者
Ashton-Rickardt, PG [1 ]
机构
[1] Univ Chicago, Ben May Inst Canc Res, Dept Pathol, Comm Immunol, Chicago, IL 60637 USA
[2] Univ Chicago, Ben May Inst Canc Res, Dept Pathol, Comm Dev Biol, Chicago, IL 60637 USA
关键词
D O I
10.1038/ni1104-1097
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Many models have been put forth to explain the function of CD4 T cell help in primary and memory CD8 T cell generation. New evidence suggests the licensing model may be the most physiologically relevant.
引用
收藏
页码:1097 / 1098
页数:2
相关论文
共 13 条
[1]   Cutting edge:: Conventional CD8α+ dendritic cells are generally involved in priming CTL immunity to viruses [J].
Belz, GT ;
Smith, CM ;
Eichner, D ;
Shortman, K ;
Karupiah, G ;
Carbone, FR ;
Heath, WK .
JOURNAL OF IMMUNOLOGY, 2004, 172 (04) :1996-2000
[2]   Help for cytotoxic-T-cell responses is mediated by CD40 signalling [J].
Bennett, SRM ;
Carbone, FR ;
Karamalis, F ;
Flavell, RA ;
Miller, JFAP ;
Heath, WR .
NATURE, 1998, 393 (6684) :478-480
[3]   Helping the CD8+ T-cell response [J].
Bevan, MJ .
NATURE REVIEWS IMMUNOLOGY, 2004, 4 (08) :595-602
[4]   A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory [J].
Bourgeois, C ;
Rocha, B ;
Tanchot, C .
SCIENCE, 2002, 297 (5589) :2060-2063
[5]   Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells [J].
Kaech, SM ;
Tan, JT ;
Wherry, EJ ;
Konieczny, BT ;
Surh, CD ;
Ahmed, R .
NATURE IMMUNOLOGY, 2003, 4 (12) :1191-1198
[6]   CD40-deficient, influenza-specific CD8 memory T cells develop and function normally in a CD40-sufficient environment [J].
Lee, BO ;
Hartson, L ;
Randall, TD .
JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 198 (11) :1759-1764
[7]  
Petschner F, 1998, EUR J IMMUNOL, V28, P560, DOI 10.1002/(SICI)1521-4141(199802)28:02<560::AID-IMMU560>3.0.CO
[8]  
2-Q
[9]   A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell [J].
Ridge, JP ;
Di Rosa, F ;
Matzinger, P .
NATURE, 1998, 393 (6684) :474-478
[10]   T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions [J].
Schoenberger, SP ;
Toes, REM ;
van der Voort, EIH ;
Offringa, R ;
Melief, CJM .
NATURE, 1998, 393 (6684) :480-483