Antibiotic resistance among enterococcal strains isolated from clinical specimens

被引:18
作者
Barisic, Z
Punda-Polic, V
机构
[1] Inst Publ Hlth, Split 21000, Croatia
[2] Univ Hosp, Split, Croatia
[3] Univ Split, Sch Med, Split, Croatia
关键词
antimicrobial resistance; enterococci; community-acquired infections;
D O I
10.1016/S0924-8579(00)00197-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The distribution and resistance patterns of clinical isolates of enterococci from hospital patients were compared with those obtained from outpatients. Of 235 enterococcal isolates 212 (90.2%) were identified as Enterococcus faecalis and 23 (9.8%) as E. faecium. E. faecium occurred more frequently in specimens from hospitalized patients than from outpatients (P < 0.001). Over 90% of all E. faecalis isolates were susceptible to ampicillin. Resistance to ampicillin occurred in 66.7% of hospital strains of E. faecium. High-level resistance to gentamicin (MIC > 500 mg/l) was seen in 37.03% of inpatients' and in 11.5% of outpatients' E. faecalis isolates and in 76.2% of hospital isolates of E. faecium. High-level streptomycin resistance (MIC > 2000 mg/l) occurred in 52.8% of E. faecalis and 76.2% of E. faecium hospital isolates. There were no isolates resistant to vancomycin. The community acquired strains isolated from outpatients were more susceptible than isolates from hospitalized patients to all antimicrobial agents tested. (C) 2000 Published by Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:65 / 68
页数:4
相关论文
共 18 条
[1]   Vancomycin resistance: Status quo and quo vadis [J].
Endtz, HP ;
van den Braak, N ;
Verbrugh, HA ;
van Belkum, A .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1999, 18 (10) :683-690
[2]  
Facklam Richard R., 1995, P308
[3]   IDENTIFICATION OF ENTEROCOCCUS SPECIES ISOLATED FROM HUMAN INFECTIONS BY A CONVENTIONAL TEST SCHEME [J].
FACKLAM, RR ;
COLLINS, MD .
JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (04) :731-734
[4]  
GATUS BJ, 1996, ANAL VIRTO DATA INT
[5]   FREQUENCY AND ANTIMICROBIAL SUSCEPTIBILITY OF CLINICAL ISOLATES OF ENTEROCOCCI [J].
GUINEY, M ;
URWIN, G .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1993, 12 (05) :362-366
[6]   Emerging resistance in Enterococcus spp. [J].
Heath, CH ;
Blackmore, TK ;
Gordon, DL .
MEDICAL JOURNAL OF AUSTRALIA, 1996, 164 (02) :116-&
[7]   THE ENTEROCOCCUS - PUTTING THE BUG IN OUR EARS [J].
HOFFMANN, SA ;
MOELLERING, RC .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (05) :757-761
[8]  
Kalenic S, 1997, Lijec Vjesn, V119, P298
[9]   ENTEROCOCCAL URINARY-TRACT INFECTIONS IN A TEACHING HOSPITAL [J].
LEMOINE, L ;
HUNTER, PR .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1987, 6 (05) :574-575
[10]   THE LIFE AND TIMES OF THE ENTEROCOCCUS [J].
MURRAY, BE .
CLINICAL MICROBIOLOGY REVIEWS, 1990, 3 (01) :46-65