Isomerization of dimeric 2,9-disubstituted 1-oxa-quinolizidine alkaloids and structural revision of araguspongines B and E, isolated from a marine sponge of Xestospongia sp.

被引：18

作者：

Kobayashi, M

Miyamoto, Y

Aoki, S

Murakami, N

Kitagawa, I

In, Y

Ishida, T

机构：

[1] Osaka Univ, Fac Pharmaceut Sci, Osaka 565, Japan

[2] Osaka Univ Pharmaceut Sci, Osaka 56911, Japan

来源：

HETEROCYCLES | 1998年 / 47卷 / 01期

关键词：

D O I：

10.3987/COM-97-S(N)4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isomerization reaction of araguspongines B (1), D (2), and E (3) having dimeric 2,9-disubstituted 1-oxaquinolizidine moiety was studied in detail. Conformational aspects of 1, 2, and 3 were also analyzed on the basis of NMR and X-ray crystallographic analysis. The C-9 stereochemistry of 1 and 3 was revised.

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页码：195 / 203

页数：9

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