Dendritic vectors for gene transfection

被引：153

作者：

Guillot-Nieckowski, Marine ^{[1
]}

Eisler, Sara ^{[1
]}

Diederich, Francois ^{[1
]}

机构：

[1] ETH, HCI, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

NEW JOURNAL OF CHEMISTRY | 2007年 / 31卷 / 07期

关键词：

D O I：

10.1039/b614877h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The wonderful versatility of dendritic structures is demonstrated by their ability to act as efficient gene transfection vectors. This review will tell the story of how dendrimers came to be exploited for gene delivery, outline the different types of structures that have proven to be successful vectors and demonstrate how structural variation is being used as a tool to increase efficiency and probe structure-activity relationships.

引用

页码：1111 / 1127

页数：17

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