Difficulties in recruiting older people in clinical trials: An examination of barriers and solutions

被引：84

作者：

Ridda, I. ^{[1
]}

MacIntyre, C. R. ^{[2
]}

Lindley, R. I. ^{[3
]}

Tan, T. C. ^{[4
,5
]}

机构：

[1] Childrens Hosp, NCIRS, Kerry Packer Inst Child Hlth Res, Sydney, NSW 2145, Australia

[2] Univ New S Wales, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia

[3] Univ Sydney, Discipline Med Geriatr Med, Sydney, NSW 2006, Australia

[4] Univ New S Wales, Sch Med Sci, Sydney, NSW 2052, Australia

[5] Westmead Hosp, Dept Cardiol, Westmead, NSW 2145, Australia

来源：

VACCINE | 2010年 / 28卷 / 04期

关键词：

Older people; Barriers to recruitment in clinical trials; Solutions to recruitment in clinical trials; COMMUNITY-BASED RESEARCH; ELDERLY PERSONS; STRATEGIES; RETENTION; LESSONS; WOMEN; PARTICIPANTS; POPULATION; CHALLENGES; PREVENTION;

D O I：

10.1016/j.vaccine.2009.10.081

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Limited information exists regarding optimal methods for the recruitment and retention of older people in clinical trials The aim of this review is to identify common barriers to the recruitment of older people in clinical trials and to propose solutions to overcome these barriers A review of literature was performed to identify common difficulties in recruiting older people This in combination with Our experience during recruitment for a randomized control trial, have highlighted numerous barriers Population-specific recruitment strategies. simple informed-consent processes. and effective communication between the researcher and subject are effective strategies to overcome these barriers (C) 2009 Elsevier Ltd All rights reserved

引用

页码：901 / 906

页数：6

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