Novel ent-abietane diterpenoids from Isodon eriocalyx var. laxiflora

被引：22

作者：

Niu, XM

Li, SH

Zhao, QS

Mei, SX

Lin, ZW

Sun, HD ^{[1
]}

Lu, Y

Wang, C

Zheng, QT

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, Key Lab Phytochem & Plant Resources, Kunming 650204, Yunnan, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2003年 / 86卷 / 02期

关键词：

D O I：

10.1002/hlca.200390031

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two novel ent-abietane diterpenoids, 3alpha,20-epoxy-6beta-hydroxy-1,7-dioxo-ent-abiet-15(17)-en-16-oic acid (1) and ent-abieta-7,15(17)-diene-3beta,16,18-triol (2) were isolated from Isodon eriocalyx var. laxiflora. Their structures were determined by extensive spectroscopic analysis and confirmed by X-ray crystallography. Compound 1 is an unprecedented example that establishes that a naturally occurring ent-abietane diterpenoid can have an oxygenation pattern almost identical to those of 3alpha,20-epoxy-ent-kaurane diterpenoids.

引用

页码：299 / 306

页数：8

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