Embryonic stem-cell culture as a tool for developmental cell biology

被引：97

作者：

Nishikawa, Shin-Ichi ^{[1
]}

Jakt, Lars Martin ^{[1
]}

Era, Takumi ^{[1
]}

机构：

[1] Ctr Dev Biol, Lab Stem Cell Res, Chuo Ku, Kobe, Hyogo 6500047, Japan

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2007年 / 8卷 / 06期

关键词：

D O I：

10.1038/nrm2189

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The cell biology of the early processes of mammalian embryogenesis, such as germ-layer formation, has been technically challenging to study owing to the size and accessibility of mammalian embryos. Embryonic stem cells, which can generate the three germ layers in vitro, are useful for studying embryogenesis at the cellular level. So, how can the study of embryonic stem cells and their differentiation provide a deeper understanding of the cell biology of early development?

引用

页码：502 / 507

页数：6

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