Salicylate induction of phenotypic resistance to quinolones in Serratia marcescens

被引：22

作者：

Berlanga, M ^{[1
]}

Viñas, M ^{[1
]}

机构：

[1] Univ Barcelona, Microbiol Unit, E-08907 Barcelona, Spain

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2000年 / 46卷 / 02期

关键词：

D O I：

10.1093/jac/46.2.279

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The influence of salicylic acid on the permeability and susceptibility of Serratia marcescens to both nalidixic acid and ciprofloxacin was studied, as well as the effect of salicylate on outer membrane proteins and lipopolysaccharide. As salicylic acid concentration increased, ciprofloxacin accumulation decreased with a concomitant, previously observed, reduction in the porin content of the outer membrane. Resistance to ciprofloxacin and nalidixic acid was enhanced when bacteria grew in the presence of salicylic acid.

引用

收藏

页码：279 / 282

页数：4

相关论文

共 11 条

[1] POTENTIATION OF SUSCEPTIBILITY TO AMINOGLYCOSIDES BY SALICYLATE IN ESCHERICHIA-COLI [J].

AUMERCIER, M ;

MURRAY, DM ;

ROSNER, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1990, 34 (05) :786-791

[2] SALICYLATE INDUCTION OF ANTIBIOTIC-RESISTANCE IN ESCHERICHIA-COLI - ACTIVATION OF THE MAR OPERON AND A MAR-INDEPENDENT PATHWAY [J].

COHEN, SP ;

LEVY, SB ;

FOULDS, J ;

ROSNER, JL .

JOURNAL OF BACTERIOLOGY, 1993, 175 (24) :7856-7862

[3] DECREASED PERMEATION OF CEPHALOSPORINS THROUGH THE OUTER-MEMBRANE OF ESCHERICHIA-COLI GROWN IN SALICYLATES [J].

FOULDS, J ;

MURRAY, DM ;

CHAI, T ;

ROSNER, JL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (04) :412-417

[4] Growth in the presence of salicylate increases fluoroquinolone resistance in Staphylococcus aureus [J].

Gustafson, JE ;

Candelaria, PV ;

Fisher, SA ;

Goodridge, JP ;

Lichocik, TM ;

McWilliams, TM ;

Price, CTD ;

O'Brien, FG ;

Grubb, WB .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (04) :990-992

[5] Bactericidal index: a new way to assess quinolone bactericidal activity in vitro [J].

Morrissey, I .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (06) :713-717

[6] A COMPARISON OF METHODS USED FOR MEASURING THE ACCUMULATION OF QUINOLONES BY ENTEROBACTERIACEAE, PSEUDOMONAS-AERUGINOSA AND STAPHYLOCOCCUS-AUREUS [J].

MORTIMER, PGS ;

PIDDOCK, LJV .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1991, 28 (05) :639-653

[7] PHENOTYPIC CHARACTERIZATION OF QUINOLONE-RESISTANT MUTANTS OF ENTEROBACTERIACEAE SELECTED FROM WILD-TYPE, GYRA-TYPE AND MULTIPLY-RESISTANT (MARA)-TYPE STRAINS [J].

PIDDOCK, LJV ;

HALL, MC ;

WALTERS, RN .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1991, 28 (02) :185-198

[8]

PUIG M, 1995, MICROBIOLOGICA, V18, P385

[9] OUTER-MEMBRANE PROTEINS FROM SERRATIA-MARCESCENS [J].

PUIG, M ;

FUSTE, C ;

VINAS, M .

CANADIAN JOURNAL OF MICROBIOLOGY, 1993, 39 (01) :108-111

[10] NONHERITABLE RESISTANCE TO CHLORAMPHENICOL AND OTHER ANTIBIOTICS INDUCED BY SALICYLATES AND OTHER CHEMOTACTIC REPELLENTS IN ESCHERICHIA-COLI K-12 [J].

ROSNER, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (24) :8771-8774