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Controlling the double helix

被引：799
作者：
Felsenfeld, G
Groudine, M
机构：
[1] NIDDKD, Mol Biol Lab, NIH, Bethesda, MD 20892 USA
[2] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98109 USA
[3] Univ Washington, Sch Med, Dept Radiat Oncol, Seattle, WA 98195 USA
来源：
NATURE | 2003年 / 421卷 / 6921期
关键词：
D O I：
10.1038/nature01411
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Chromatin is the complex of DNA and proteins in which the genetic material is packaged inside the cells of organisms with nuclei. Chromatin structure is dynamic and exerts profound control over gene expression and other fundamental cellular processes. Changes in its structure can be inherited by the next generation, independent of the DNA sequence itself.
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页码：448 / 453
页数：7
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