Treatment of latent tuberculosis infection in patients aged ≥35 years

被引：28

作者：

Gilroy, SA

Rogers, MAM

Blair, DC

机构：

[1] SUNY Upstate Med Univ, Dept Med, Div Infect Dis, Syracuse, NY 13210 USA

[2] SUNY Upstate Med Univ, Dept Epidemiol, Syracuse, NY 13210 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2000年 / 31卷 / 03期

关键词：

D O I：

10.1086/314037

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Treating patients aged greater than or equal to 35 years for tuberculosis infection has been controversial because of the hepatotoxic effects of isoniazid. A 2-year retrospective cohort study of outpatient medical records determined the completion rate in this age group and identified risk factors associated with isoniazid-associated hepatotoxicity. Isoniazid preventative therapy was well tolerated. However, toxicity occurred in women receiving concomitant medications and men who used alcohol.

引用

页码：826 / 829

页数：4

共 14 条

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