Marginal analyses of longitudinal data with an informative pattern of observations

被引:11
作者
Farewell, D. M. [1 ]
机构
[1] Cardiff Univ, Dept Primary Care & Publ Hlth, Sch Med, Cardiff CF14 4YS, S Glam, Wales
关键词
Generalized estimating equation; Informative observation; Linear increments; Longitudinal data; SEMIPARAMETRIC REGRESSION; ESTIMATING EQUATIONS; REPEATED OUTCOMES; BINARY DATA; DISCRETE; MODELS; SIZE;
D O I
10.1093/biomet/asp068
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We consider solutions to generalized estimating equations with singular working correlation matrices, of which the estimator of Diggle et al. (2007) is a special case. We give explicit conditions for consistent estimation when the pattern of observations may be informative. In such cases, simulations reveal reduced bias and reduced mean squared error compared with existing alternatives. A study of peritoneal dialysis is used to illustrate the methodology.
引用
收藏
页码:65 / 78
页数:14
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