Therapeutic patents for topical and transdermal drug delivery systems

被引:10
作者
Chen, HY [1 ]
Fang, JY [1 ]
机构
[1] Taipei Med Coll, Grad Inst Pharmaceut Sci, Taipei, Taiwan
关键词
absorption enhancer; delivery system; formulation; patch formulation; transdermal formulation;
D O I
10.1517/13543776.10.7.1035
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
For more than 30 years techniques of delivering drugs through skin have been elaborated as clinically relevant methods to administer therapeutic agents. The great contributions of transdermal and topical administrations on clinical therapeutics are firmly based on their distinctive properties. Progress in new technologies and compound is continuously stimulating the growth and revolution of topical and transdermal administration. This review summarises recent developments in the design of formulations and the patent literature in the area of topical and transdermal drug delivery systems.
引用
收藏
页码:1035 / 1043
页数:9
相关论文
共 63 条
[1]   Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages [J].
Abe, Y ;
Hashimoto, S ;
Horie, T .
PHARMACOLOGICAL RESEARCH, 1999, 39 (01) :41-47
[2]   Iontophoresis and electroporation: comparisons and contrasts [J].
Banga, AK ;
Bose, S ;
Ghosh, TK .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1999, 179 (01) :1-19
[3]   Topical tacrolimus (FK 506): A new milestone in the management of atopic dermatitis [J].
Bieber, T .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1998, 102 (04) :555-557
[4]  
Carlotti ME, 1999, J COSMET SCI, V50, P281
[5]  
CASTELL JV, 1997, AM J PHYSIOL, V273, P139
[6]  
Chen H, 1999, ANTICANCER RES, V19, P3675
[7]  
CRANDALL WT, 1998, Patent No. 9803641
[8]   Transdermal penetration enhancers: Applications, limitations, and potential [J].
Finnin, BC ;
Morgan, TM .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1999, 88 (10) :955-958
[9]   Treatment of atopic dermatitis: Role of tacrolimus ointment as a topical noncorticosteroidal therapy [J].
Fleischer, AB .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1999, 104 (03) :S126-S130
[10]   Assessment of value and applications of in vitro testing of topical dermatological drug products [J].
Flynn, GL ;
Shah, VP ;
Tenjarla, SN ;
Corbo, M ;
DeMagistris, D ;
Feldman, TG ;
Franz, TJ ;
Miran, DR ;
Pearce, DM ;
Sequeira, JA ;
Swarbrick, J ;
Wang, JCT ;
Yacobi, A ;
Zatz, JL .
PHARMACEUTICAL RESEARCH, 1999, 16 (09) :1325-1330