Depletion of ovarian follicles with age in chimpanzees: Similarities to humans

被引：50

作者：

Jones, K. P.

Walker, L. C.

Anderson, D.

Lacreuse, A.

Robson, S. L.

Hawkes, K.

机构：

[1] Univ Utah, Sch Med, Salt Lake City, UT 84132 USA

[2] Dept Obstet & Gynecol, Salt Lake City, UT 84132 USA

[3] Emory Univ, Yerkes Natl Primate Res Ctr, Atlanta, GA 30329 USA

[4] Univ Massachusetts, Dept Psychol, Amherst, MA 01003 USA

[5] Univ Utah, Dept Anthropol, Salt Lake City, UT 84112 USA

来源：

BIOLOGY OF REPRODUCTION | 2007年 / 77卷 / 02期

关键词：

aging; chimpanzee; follicle; ovary;

D O I：

10.1095/biolreprod.106.059634

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We retrieved ovarian sections taken from necropsies of 19 captive chimpanzees (Pan troglodytes) aged 0-47 yr, counted the number of primordial follicles in each, and compared the rate of decline in numbers to declines previously documented in humans. The follicular depletion rate in this sample was indistinguishable from that shown across the same ages in classic human data sets. This result supports earlier suggestions that ovarian senescence occurs at the same ages in chimpanzees and humans, implying that the influence of declining ovarian function on other physiologic systems may be distinctively buffered in humans.

引用

页码：247 / 251

页数：5

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