Longithorones, unique prenylated para- and metacyclophane type quinones from the tunicate Aplidium longithorax

被引：79

作者：

Fu, X ^{[1
]}

Hossain, MB ^{[1
]}

Schmitz, FJ ^{[1
]}

vanderHelm, D ^{[1
]}

机构：

[1] UNIV OKLAHOMA,DEPT CHEM & BIOCHEM,NORMAN,OK 73019

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 12期

关键词：

D O I：

10.1021/jo9702204

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A group of nine farnesylated quinones (1-9) featuring new macrocyclic skeletons formed by farnesyl units bridging the quinones in the meta or para positions have been isolated from a tunicate, Aplidium longithorax. Three of these are monomeric C-21 compounds, while the remainder are dimeric C-42 products. These meta- and paracyclophane type compounds all show atropisomerism and their biogenesis appears to involve 4 + 2 cycloadditions. Structures were determined by X-ray and spectroscopic analysis.

引用

页码：3810 / 3819

页数：10

共 31 条

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