Current management of melanoma: Benefits of surgical staging and adjuvant therapy

被引：26

作者：

McMasters, KM

Swetter, SM

机构：

[1] Univ Louisville, Div Surg Oncol, James Graham Brown Canc Ctr, Louisville, KY 40202 USA

[2] Vet Affairs Palo Alto, Palo Alto, CA USA

[3] Stanford Univ, Med Ctr, Palo Alto, CA 94304 USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2003年 / 82卷 / 03期

关键词：

skin neoplasms; staging; sentinel lymph node; drug therapy; interferon-alpha;

D O I：

10.1002/jso.10216

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Issues regarding appropriate management of stage I to III melanoma are addressed. Accurate surgical staging is critical to identifying patients who can benefit from therapeutic lymph node dissection and adjuvant therapy. Patients with primary tumors greater than or equal to1 mm thick are appropriate candidates for sentinel lymph node biopsy, and node-positive patients benefit from therapeutic lymphadenectomy. Although the overall survival benefit of high-dose interferon has been questioned, the weight of evidence supports the use of adjuvant therapy in patients with stage IIB and III disease. (C) 2003 Wiley-Liss, Inc.

引用

页码：209 / 216

页数：8

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