Orthosilicate-mediated esterification of monosubstituted phosphinic acids

被引：49

作者：

Dumond, YR ^{[1
]}

Baker, RL ^{[1
]}

Montchamp, JL ^{[1
]}

机构：

[1] Texas Christian Univ, Dept Chem, Ft Worth, TX 76129 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 21期

关键词：

D O I：

10.1021/ol006434g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Monosubstituted phosphinic acids are esterified with orthosilicates in excellent yields. Phosphinylidene-containing acids react selectively under these conditions, while disubstituted phosphinic acids and phosphonic acids remain unchanged. One-pot procedures are also described for the preparation of phosphinate esters from an alcohol. This novel method provides a convenient and general alternative to more commonly employed conditions such as diazomethane or carbodiimide.

引用

页码：3341 / 3344

页数：4

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