Total synthesis of a glyoxalase I inhibitor and its precursor, (-)-KD16-U1

被引：44

作者：

Tatsuta, K ^{[1
]}

Yasuda, S ^{[1
]}

Araki, N ^{[1
]}

Takahashi, M ^{[1
]}

Kamiya, Y ^{[1
]}

机构：

[1] Waseda Univ, Sch Sci & Engn, Dept Appl Chem, Shinjuku Ku, Tokyo 169, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 5-6期

关键词：

D O I：

10.1016/S0040-4039(97)10559-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A glyoxalase I inhibitor and (-)-KD16-U1 have been synthesized from D-ribonic acid gamma-lactone through SnCl4-promoted cyclization of a phenylsulfonyl enol silyl ether and regioselective introduction of a hydroxymethyl group. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：401 / 402

页数：2

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