Human intestinal tissue tropism of intimin epsilon O103 Escherichia coli

被引：16

作者：

Fitzhenry, RJ

Stevens, MP

Jenkins, C

Wallis, TS

Heuschkel, R

Murch, S

Thomson, M

Frankel, G

Phillips, AD

机构：

[1] Royal Free Hosp, Ctr Paediat Gastroenterol, London NW3 2QG, England

[2] Inst Anim Hlth, Compton, England

[3] Cent Publ Hlth Lab, Div Enter Pathogens, London, England

[4] Univ London Imperial Coll Sci Technol & Med, Dept Biol Sci, Ctr Mol Microbiol & Infect, London, England

来源：

FEMS MICROBIOLOGY LETTERS | 2003年 / 218卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

intimin; enteropathogenic; enterohaemorrhagic; human; O103 Escherichia coli;

D O I：

10.1016/S0378-1097(02)01182-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human intestinal in vitro organ culture was used to assess the tissue tropism of human isolates of Escherichia coli O103:H2 and O103:H- that express intimin F. Both strains showed tropism for follicle associated epithelium and limited adhesion to other regions of the small and large intestine. This is similar to the tissue tropism shown by intimin gamma enterohaemorrhagic (EHEC) O157:H7, but distinct from that of intimin a enteropathogenic (EPEC) O127:H6. (C) 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

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收藏

页码：311 / 316

页数：6

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