Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

被引:2305
作者
Cohen, Stuart H. [1 ]
Gerding, Dale N. [2 ,3 ]
Johnson, Stuart [2 ,3 ]
Kelly, Ciaran P. [4 ]
Loo, Vivian G. [5 ]
McDonald, L. Clifford [6 ]
Pepin, Jacques [7 ]
Wilcox, Mark H. [8 ,9 ]
机构
[1] Univ Calif Davis, Med Ctr, Dept Internal Med, Div Infect & Immunol Dis, Sacramento, CA 95817 USA
[2] Loyola Univ Chicago Stritch Sch Med, Res Serv, Vet Affairs Edward Hines Jr Hosp, Maywood, IL USA
[3] Loyola Univ Chicago Stritch Sch Med, Div Infect Dis, Dept Med, Maywood, IL USA
[4] Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA 02215 USA
[5] McGill Univ, Dept Microbiol, Ctr Hlth, Montreal, PQ H3A 2T5, Canada
[6] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Natl Ctr Preparedness Detect & Control Infect Dis, Atlanta, GA USA
[7] Univ Sherbrooke, Dept Microbiol & Infect Dis, Quebec City, PQ, Canada
[8] Univ Leeds, Dept Microbiol, Leeds Teaching Hosp Natl Hlth Serv Trust, Leeds LS2 9JT, W Yorkshire, England
[9] Univ Leeds, Inst Mol & Cellular Biol, Leeds LS2 9JT, W Yorkshire, England
关键词
ANTIBIOTIC-ASSOCIATED DIARRHEA; RANDOMIZED CONTROLLED-TRIAL; PROTON PUMP INHIBITORS; TANDEM-REPEAT ANALYSIS; RISK-FACTORS; HOSPITALIZED-PATIENTS; TOXIN-A; INTRAVENOUS IMMUNOGLOBULIN; ENVIRONMENTAL CONTAMINATION; PSEUDOMEMBRANOUS COLITIS;
D O I
10.1086/651706
中图分类号
R1 [预防医学、卫生学];
学科分类号
100235 [预防医学];
摘要
Since publication of the Society for Healthcare Epidemiology of America position paper on Clostridium difficile infection in 1995, significant changes have occurred in the epidemiology and treatment of this infection. C. difficile remains the most important cause of healthcare-associated diarrhea and is increasingly important as a community pathogen. A more virulent strain of C. difficile has been identified and has been responsible for more-severe cases of disease worldwide. Data reporting the decreased effectiveness of metronidazole in the treatment of severe disease have been published. Despite the increasing quantity of data available, areas of controversy still exist. This guideline updates recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management. Infect Control Hosp Epidemiol 2010; 31(5):431-455
引用
收藏
页码:431 / 455
页数:25
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